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Doctor Who is a science fiction programme first started by the BBC in 1969. It tells the never ending tale of a last of his kind, Timelord ( a type of alien) who travels through time in his little-to-eye police phone box called the TARDIS: Time and relative dimension in space; The TARDIS is bigger on the inside. The Doctor has lived 1100 years and throughout these extensive years has saved millions of lives using only his vast knowledge of the universe, being a Timelord this knowledge is bestowed on him as a child; oh yes and with the help of his clever little Sonic Screwdriver. Along with a chain of human companions, the Doctor travels time and space only to save worlds and civilizations.
The reason for the longevity of the show is because, when the Doctor is dying, he uses this trick Timelords evolved to stay alive, Regeneration. Using this, every cell in his body dies and is replaced with new cells, resulting in an overall change in appearance and personality. The Doctor has regenerated a total of 11 time since the show first aired; the first being William Hartnell and the current being Matt Smith.